Medicine

Biomedical

Seminal papers in urology: two-year outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for refractory urgency urinary incontinence: a Randomized Trial


AbstractIn this critical review, we explore the study design, strengths and limitations of the paper: “Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: A Randomized Trial.” The paper reports 24 month follow-up data of the landmark ROSETTA trial. This multi-centre, open-labelled parallel randomise...
1 month ago

Biomedical

Prediction of biochemical recurrence after laparoscopic radical prostatectomy


Abstract Background Radical prostatectomy (RP) has been considered primary treatment for localized prostate cancer. Biochemical recurrence (BCR) occur approximately 20–30% in five year after RP. We aim to develop a novel nomogram to predict BCR-free survival (BCRFS) and performed external validati...
1 month ago

Biomedical

Does the biomarker search paradigm need re-booting?


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1 month ago

Biomedical

Symptomatic renal papillary varicosities and medullary nephrocalcinosis


Abstract Background Nephrocalcinosis is often asymptomatic but can manifest with renal colic or hematuria. There is no reported association between nephrocalcinosis and renal vascular malformations, which may also be a source of hematuria. We herein present a case of a patient with hematuria related...
1 month ago

Biomedical

An uncommon mimicker of renal malignancy: IgG4-related disease


Abstract Background Increased usage of cross sectional imaging for a variety of indications, in particular CT imaging, has led to an increased detection of renal and ureteric masses. Benign ureteric masses are rare, with 95% of identified tumours consisting of transitional cell carcinoma (TCC). IgG4...
1 month ago

Biomedical

Seminal papers in urology: anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence


AbstractIn this critical review, we explore the study design, strengths, and limitations of landmark trial “Anticholinergic therapy vs. onabotulinumtoxinA for urgency urinary incontinence”. This trial was the first to directly compare two key treatment options for urge urinary incontinence – anticholinergic medication and intravesical botox, and still influen...
1 month ago

Biomedical

Prevalence and profile of headache in school-going adolescents aged 10 – 19 years in Benin City: a cross sectional survey


IntroductionAdolescent headaches significantly impact their daily functioning, academic performance, and quality of life. The occurrence of headaches is influenced by genetics, psychological stressors, and environmental exposures. Understanding these influences is crucial for effective management strategies.AimTo determine the prevalence, characteristics, and associated factors of headache...
1 month ago

Biomedical

Québec health care professionals’ perspectives on organ donation after medical assistance in dying


Background Medical assistance in dying (MAID) has been legal in Québec since December 2015 and in the rest of Canada since July 2016. Since then, more than 60 people have donated their organs after MAID. Such donations raise ethical issues about respect of patients’ autonomy, potential pressure to choose MAID, the information given to potential donors, the acceptability of di...
1 month ago

Biomedical

Navigating the ethical landscape of artificial intelligence in radiography: a cross-sectional study of radiographers’ perspectives


Abstract Background The integration of artificial intelligence (AI) in radiography presents transformative opportunities for diagnostic imaging and introduces complex ethical considerations. The aim of this cross-sectional study was to explore radiographers’ perspectives on the ethical implications of AI in their field and identify key concerns and potential str...
1 month ago

Biomedical

Caught you: threats to confidentiality due to the public release of large-scale genetic data sets


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1 month ago

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