Medicine

Biomedical

The Roles of Various Immune Cell Populations in Immune Response against Helminths


Helminths are multicellular parasites that are a substantial problem for both human and veterinary medicine. According to estimates, 1.5 billion people suffer from their infection, resulting in decreased life quality and burdens for healthcare systems. On the other hand, these infections may alleviate autoimmune diseases and allergy symptoms. The immune system is programmed to combat infec...
3 weeks ago

Biomedical

Prevalence of Leishmaniasis among Blood Donors: A Systematic Review and Meta-Analysis


Our study seeks to provide a comprehensive assessment of leishmaniasis prevalence among blood donors, employing rigorous methodologies to inform public health initiatives and transfusion safety measures. A thorough literature search was conducted using electronic databases (Medline, Scopus, Web of Science, and Google Scholar) to identify the relevant studies reporting the prevalence of lei...
3 weeks ago

Biomedical

Hydrogel Use in Osteonecrosis of the Femoral Head


Osteonecrosis of the femoral head (ONFH) is a vascular disease of unknown etiology and can be categorized mainly into two types: non-traumatic and traumatic ONFH. Understanding osteogenic–angiogenic coupling is crucial for developing solutions for ONFH treatment. Hydrogels, due to their extracellular matrix (ECM)-like properties, have gained popularity for their ability to retain water,...
1 month ago

Biomedical

Case cancellations and associated factors on the day of surgery in hospitals of Wolaita Zone, South Ethiopia


Background

Cancellations of elective surgery cases are frequent and have significant negative consequences. It causes wasting of valuable resources, patient unhappiness, and psychological stress of patients. Despite this, little is known about the case cancellation and associated factors on the d...
1 month ago

Biomedical

The learning curve in endoscopic transsphenoidal skull-base surgery: a systematic review


Background

The endoscopic endonasal transsphenoidal approach (EETA) has revolutionized skull-base surgery; however, it is associated with a steep learning curve (LC), necessitating additional attention from surgeons to ensure patient safety and surgical efficacy. The current literature is c...
1 month ago

Biomedical

Time-to-surgery paradigms: wait time and surgical outcomes in critically Ill patients who underwent emergency surgery for gastrointestinal perforation


Background

Waiting time for emergency abdominal surgery has been known to be linked to mortality. However, there is no clear consensus on the appropriate timing of surgery for gastrointestinal perforation. We investigated the association between wait time and surgical outcomes in emergency abdominal surgery.

Biomedical

Surgical mortality in patients in extremis: futility in emergency abdominal surgery


This scoping review evaluates the prognostic impact and describes suturing tools for mesenteric closure after laparoscopic right hemicolectomy (LRH). A systematic search of medical databases identified 7 relevant publications. The evidence does not support routine closure of mesenteric defects after LRH. Use of polymer ligation clips showed promising results in a small trial, but further research ...
1 month ago

Biomedical

The value of mesenteric closure after laparoscopic right hemicolectomy: a scoping review


To evaluate the prognostic impact and describe suturing tools of mesenteric closure after laparoscopic right hemicolectomy (LRH), a scoping review was conducted. PubMed, Embase, Cochrane library, Web of Science, and Scopus databases were searched for publications relating to mesenteric closure data and tools. A total of 7 publications were identified, with 5 focused on prognostic impact and 4 refe...
1 month ago

Biomedical

Clinical results with a multifocal intraocular lens with a novel optical design


Background

To evaluate the optical performance and safety of a new multifocal lens with a novel optical design featuring two additional foci (or intensifiers) in patients with cataract and presbyopia.

Methods

In this single-center, non-randomized prospective observat...
1 month ago

Biomedical

Preoperative investigation practices for elective surgical patients: clinical audit


Background

The findings of pre-operative investigations help to identify risk factors that may affect the course of surgery or post-operative recovery by contributing to informed consent conversations between the surgical team and the patient, as well as guiding surgical and anesthetic planning. Certainly, preoperative tests are valuable...
1 month ago

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