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Biomedical

The Implications of Early Adversity Even Before Birth

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Charles A. Nelson

Charles A. Nelson

Laboratories of Cognitive Neuroscience, Department of Pediatrics, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts


  Peer Reviewed

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© attribution CC-BY

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rating
433 Views

Added on

2024-10-22

Doi: http://dx.doi.org/10.1001/jamanetworkopen.2019.20030

Related Subjects
Anatomy
Biochemistry
Epidemiology
Genetics
Neuroscience
Psychology
Oncology
Medicine
Musculoskeletal science
Pediatrics
Pathology
Pharmacology
Physiology
Psychiatry
Primary care
Women and reproductive health

Abstract

This study examines how prenatal exposure to maternal psychological distress, such as stress, anxiety, and depression, can impact fetal brain development. Findings suggest that these stressors may lead to changes in brain volume and structure, with potential long-term effects on behavioral development. The research highlights the importance of maternal mental health during pregnancy, indicating that early interventions could mitigate some of these effects, though further investigation is needed to understand the full scope of these impacts.

Key Questions and Answers

1. What impact does prenatal exposure to maternal psychological distress have on fetal brain development?

Maternal anxiety, stress, and depression during pregnancy are linked to changes in fetal brain structure, including reduced brain volume and increased gyrification.

2. How early do the effects of prenatal adversity begin?

These effects may start as early as the first trimester, though the exact timing remains unclear.

3. Can postnatal environments mitigate the prenatal effects of psychological distress?

It is uncertain whether postnatal interventions can fully compensate for prenatal brain changes, though they may help to some extent.

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ARTICLE USAGE


Article usage: Oct-2024 to May-2025
Show by month Manuscript Video Summary
2025 May 40 40
2025 April 86 86
2025 March 63 63
2025 February 46 46
2025 January 63 63
2024 December 56 56
2024 November 57 57
2024 October 22 22
Total 433 433
Show by month Manuscript Video Summary
2025 May 40 40
2025 April 86 86
2025 March 63 63
2025 February 46 46
2025 January 63 63
2024 December 56 56
2024 November 57 57
2024 October 22 22
Total 433 433
Related Subjects
Anatomy
Biochemistry
Epidemiology
Genetics
Neuroscience
Psychology
Oncology
Medicine
Musculoskeletal science
Pediatrics
Pathology
Pharmacology
Physiology
Psychiatry
Primary care
Women and reproductive health
copyright icon

© attribution CC-BY

  • 0

rating
433 Views

Added on

2024-10-22

Doi: http://dx.doi.org/10.1001/jamanetworkopen.2019.20030

Related Subjects
Anatomy
Biochemistry
Epidemiology
Genetics
Neuroscience
Psychology
Oncology
Medicine
Musculoskeletal science
Pediatrics
Pathology
Pharmacology
Physiology
Psychiatry
Primary care
Women and reproductive health

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