Women and reproductive health

Biomedical

Factors Associated with Progression to Preeclampsia with Severe Features in Pregnancies Complicated by Mild Hypertensive Disorders


In this retrospective cohort study, we aimed to investigate the variables associated with progression to preeclampsia with severe features in parturients already diagnosed with mild hypertensive disorders of pregnancy. The study was conducted in a single university-affiliated medical center between 2018 and 2020. All women admitted due to hypertensive disorders were included. Data collecte...
4 weeks ago

Biomedical

Inter- and intra-rater reproducibility of quantitative T1 measurement using semiautomatic region of interest placement in myometrium


Purpose

This study aimed to investigate the inter- and intraobserver reproducibility of quantitative T1 (qT1) measurements using manual and semiautomatic region of interest (ROI) placements. We hypothesized the usefulness of the semiautomatic method, which utilizes a three-di...
1 month ago

Biomedical

Development of a nomogram for the prediction of complicated appendicitis during pregnancy


This study explores the electrochemical synthesis of S-oxide metabolites from phenothiazine-containing antipsychotic medications. The researchers investigated the structure-electroactivity relationship and cyclic voltammetry behavior of 2-chlorophenothiazine (2CPTZ) and chlorpromazine (CPZ). They successfully synthesized and isolated the sulfoxide and sulfone metabolites using constant current ele...
1 month ago

Biomedical

Electronic Fetal Monitoring—Imperfect but Opportunities for Improvement


Electronic fetal monitoring (EFM) has limitations in detecting fetal hypoxia and acidemia, and clinicians often do not act on abnormal readings. Recent studies suggest that improving clinician training, refining monitoring algorithms, and establishing standardized protocols can help prevent neonatal encephalopathy. Despite its flaws, EFM presents opportunities to enhance neonatal outcomes through ...
3 months ago

Biomedical

Pregnancy and Risk of Intracerebral Hemorrhage


The study highlights pregnancy's role in increasing the risk of intracerebral hemorrhage (ICH), especially within the first 12 weeks postpartum. Key risk factors include chronic hypertension, gestational hypertension, and preeclampsia. Treatment strategies focus on blood pressure control, the use of low-dose aspirin for high-risk women, and managing coagulation issues. Timely diagnosis and neuroim...
3 months ago

Biomedical

The Implications of Early Adversity Even Before Birth


This study examines how prenatal exposure to maternal psychological distress, such as stress, anxiety, and depression, can impact fetal brain development. Findings suggest that these stressors may lead to changes in brain volume and structure, with potential long-term effects on behavioral development. The research highlights the importance of maternal mental health during pregnancy, indicating th...
3 months ago

Biomedical

Determinants of Cervical Cancer Screening among Female Health Professionals in Harar Town, Eastern Ethiopia: A Cross‐Sectional Study


Background. Early screening for cervical cancer is a key life‐saving intervention in reducing maternal mortality and morbidity. Despite the high burden of cervical cancer, the coverage of cervical cancer screening is low in developing countries, including Ethiopia. There is a paucity of information on the utilization of cervical cancer screening among female health professionals in eastern Ethio...
3 months ago

Biomedical

CER818: A Highly Specific and Sensitive HPV L1 High‐Risk Serological Lateral Flow Rapid Test for Early Detection of Cervical Cancer and Its Precursor Lesions


Objective: The objective of the study is to validate a new human papillomavirus (HPV) L1 high‐risk specific serological assay in a case‐control study.Methods: Serum samples of 138 patients (cervical intraepithelial neoplasia (CIN) 1, 2, and 3 and cervical cancer), 21 vaccinees, and 246 female controls were tested for the presence of HPV L1 high‐risk specific antibodies.Results: HPV L1 high...
3 months ago

Biomedical

Time trends in contraceptive prescribing in UK primary care 2000– 2018: a repeated cross-sectional study


Background Over the last 20 years, new contraceptive methods became available and incentives to increase contraceptive uptake were introduced. We aimed to describe temporal trends in non-barrier contraceptive prescribing in UK primary care for the period 2000–2018. Methods A repeated cross-sectional study using patient data from the IQVIA Medical Research Data (IMRD) database. The proportio...
2 years ago

Biomedical

Predictors associated with low-risk women’s pre-labour intention for intrapartum pain relief: a cross-sectional study


Background Pregnant women have preferences about how they intend to manage labour pain. Unmet intentions can result in negative emotions and/or birth experiences. Objective To examine the antenatal level of intention for intrapartum pain relief and the factors that might predict this intention. Design A cross-sectional online survey-based study. Setting and participants 414 healthy pregnant wo...
2 years ago

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