Medicine

Biomedical

Caught you: threats to confidentiality due to the public release of large-scale genetic data sets


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1 month ago

Biomedical

Mother’s Curse effects on lifespan and aging


The Mother’s Curse hypothesis posits that mothers curse their sons with harmful mitochondria, because maternal mitochondrial inheritance makes selection blind to mitochondrial mutations that harm only males. As a result, mitochondrial function may be evolutionarily optimized for females. This is an attractive explanation for ubiquitous sex differences in lifespan and aging, given the pre...
1 month ago

Biomedical

Advancing longevity research through decentralized science


In an era marked by scientific stagnation, Decentralized Science (DeSci) challenges the inefficiencies of traditional funding and publishing systems. DeSci employs blockchain technology to address the misalignment of incentives in academic research, emphasizing transparency, rapid funding, and open-source principles. Centralized institutions have been linked to a deceleration of progress, which is...
1 month ago

Biomedical

An integrative approach to dementia care


As the aging population continues to increase, Alzheimer’s disease and related dementias are becoming a global health crisis. The burdens experienced by the person living with dementia, their caregivers, healthcare, and society persist unabated. Persons with dementia represent an important population in need of a tenable care plan. Caregivers need the tools with which to properly care for these ...
1 month ago

Biomedical

Aging, adaptation and maladaptation


Aging is accompanied by a dysregulation of adaptive processes. On the one hand, physiological adaptation mechanisms such as learning and memory, immune system plasticity and exercise-dependent muscle remodeling are blunted. On the other hand, several maladaptive processes increase with age including cancer, pathological cardiovascular remodeling and metabolic dysregulation. With increasing age the...
1 month ago

Biomedical

The Roles of Various Immune Cell Populations in Immune Response against Helminths


Helminths are multicellular parasites that are a substantial problem for both human and veterinary medicine. According to estimates, 1.5 billion people suffer from their infection, resulting in decreased life quality and burdens for healthcare systems. On the other hand, these infections may alleviate autoimmune diseases and allergy symptoms. The immune system is programmed to combat infections; n...
1 month ago

Biomedical

Evaluating a Dental Public-Health Game across Two Learning Contexts


Serious games have been shown to be effective learning tools in various disciplines, including dental education. Serious-game learning environments allow learners to improve knowledge and skills. GRAPHIC (Games Research Applied to Public Health with Innovative Collaboration), a serious game for dental public health, was designed to simulate a town, enabling students to apply theoretical knowledge ...
1 month ago

Biomedical

New microbes, new infections, new editor, new directions


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1 month ago

Biomedical

Prevalence of Leishmaniasis among Blood Donors: A Systematic Review and Meta-Analysis


Our study seeks to provide a comprehensive assessment of leishmaniasis prevalence among blood donors, employing rigorous methodologies to inform public health initiatives and transfusion safety measures. A thorough literature search was conducted using electronic databases (Medline, Scopus, Web of Science, and Google Scholar) to identify the relevant studies reporting the prevalence of leishmanias...
1 month ago

Biomedical

How Should Surveillance Systems Account for Concurrent Intravascular Catheters?


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1 month ago

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