Medicine

A review of reproducible and transparent research practices in urology publications from 2014 to2018

Abstract Background Reproducibility is essential for the integrity of scientific research. Reproducibility is measured by the ability of different investigators to replicate the outcomes of an original publication using the same materials and procedures. Unfortunately, reproducibility is not current...
1 week ago

Seminal papers in urology: two-year outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for refractory urgency urinary incontinence: a Randomized Trial

AbstractIn this critical review, we explore the study design, strengths and limitations of the paper: “Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: A Randomized Trial.” The paper reports 24 month follow-up data of the landmark ROSETTA trial. This multi-centre, open-labelled parallel randomise...
1 week ago

Prediction of biochemical recurrence after laparoscopic radical prostatectomy

Abstract Background Radical prostatectomy (RP) has been considered primary treatment for localized prostate cancer. Biochemical recurrence (BCR) occur approximately 20–30% in five year after RP. We aim to develop a novel nomogram to predict BCR-free survival (BCRFS) and performed external validati...
1 week ago

Does the biomarker search paradigm need re-booting?

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1 week ago

Symptomatic renal papillary varicosities and medullary nephrocalcinosis

Abstract Background Nephrocalcinosis is often asymptomatic but can manifest with renal colic or hematuria. There is no reported association between nephrocalcinosis and renal vascular malformations, which may also be a source of hematuria. We herein present a case of a patient with hematuria related...
1 week ago

An uncommon mimicker of renal malignancy: IgG4-related disease

Abstract Background Increased usage of cross sectional imaging for a variety of indications, in particular CT imaging, has led to an increased detection of renal and ureteric masses. Benign ureteric masses are rare, with 95% of identified tumours consisting of transitional cell carcinoma (TCC). IgG4...
1 week ago

Seminal papers in urology: anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence

AbstractIn this critical review, we explore the study design, strengths, and limitations of landmark trial “Anticholinergic therapy vs. onabotulinumtoxinA for urgency urinary incontinence”. This trial was the first to directly compare two key treatment options for urge urinary incontinence – anticholinergic medication and intravesical botox, and still influen...
1 week ago

Prevalence and profile of headache in school-going adolescents aged 10 – 19 years in Benin City: a cross sectional survey

IntroductionAdolescent headaches significantly impact their daily functioning, academic performance, and quality of life. The occurrence of headaches is influenced by genetics, psychological stressors, and environmental exposures. Understanding these influences is crucial for effective management strategies.AimTo determine the prevalence, characteristics, and associated factors of headache...
2 weeks ago

Québec health care professionals’ perspectives on organ donation after medical assistance in dying

Background Medical assistance in dying (MAID) has been legal in Québec since December 2015 and in the rest of Canada since July 2016. Since then, more than 60 people have donated their organs after MAID. Such donations raise ethical issues about respect of patients’ autonomy, potential pressure to choose MAID, the information given to potential donors, the acceptability of di...
3 weeks ago

Navigating the ethical landscape of artificial intelligence in radiography: a cross-sectional study of radiographers’ perspectives

Abstract Background The integration of artificial intelligence (AI) in radiography presents transformative opportunities for diagnostic imaging and introduces complex ethical considerations. The aim of this cross-sectional study was to explore radiographers’ perspectives on the ethical implications of AI in their field and identify key concerns and potential str...
3 weeks ago

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