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Transcription factors organize into functional groups on the linear genome and in 3D chromatin

Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial proximity (using chromatin conformation capture...

5 months ago

Predicting the Oxidation States of Mn ions in the Oxygen Evolving Complex of Photosystem II Using Supervised and Unsupervised Machine Learning

Serial Femtosecond Crystallography at the X-ray Free Electron Laser (XFEL) sources enabled the imaging of the catalytic intermediates of the oxygen evolution reaction of Photosystem II. However, due to the incoherent transition of the S-states, the resolved structures are a convolution from diff...

6 months ago

Lorem ipsum dolor sit amet

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Suspendisse accumsan lectus ultrices, fermentum nisl at, malesuada dolor. Donec vitae odio tincidunt risus luctus accumsan sed ac tellus. Maecenas lacus nunc, scelerisque a fermentum non, pharetra fringilla erat. Nullam et dolor interdum, cond...

1 year ago

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