Research Infinity - All Articles

No Category

Urinary bladder carcinoma with triplicate differentiations into giant cell sarcomatoid carcinoma, squamous cell carcinoma, and papillary urothelial transitional cell carcinoma: a case report

The author reports a very rare and very unique urinary bladder carcinoma. This carcinoma occurred in a 68-year-old Japanese patient who underwent cystectomy for bladder tumor. The tumor was large polypoid and ulcerated one. Histologically, the tumor consisted of the following three elements: giant cell sarcomatoid carcinoma (70% in area), squamous cell carcinoma (20% in area), and papillary urothe...
Posted 3 months ago

No Category

Hereditary succinate dehydrogenase-deficient renal cell carcinoma

...
Posted 3 months ago

Biomedical

Hereditary non-polyposis colorectal cancer (HNPCC) and its genetic basis

Hereditary non-polyposis colorectal cancer (HNPCC) and itsgenetic basis...
Posted 3 months ago

Biomedical

Evaluation and comparison of hereditary Cancer guidelines in the population

Background Family health history (FHx) is an effective tool for identifying patients at risk of hereditary cancer. Hereditary cancer clinical practice guidelines (CPG) contain criteria used to evaluate FHx and to make recommendations for genetic consultation. Comparing different CPGs used to evaluate a common set of FHx provides insight into how well the CPGs perform, the extent of agreement acro...
Posted 3 months ago

Biomedical

The knowledge of hereditary breast cancer, and attitude and intention towards genetic testing of the patients with high-risk hereditary breast cancer

Purpose: This study aimed to explore the knowledge of hereditary breast cancer (HBC) and attitudes and intention towards genetic testing of the patients with high-risk HBC, and to describe their differences according to the intention of genetic test. Methods: High-risk HBC patients (n = 138) who did not take genetic test or relevant counseling were recruited in D city, Korea. Participants complete...
Posted 3 months ago

Biomedical

A sheep in wolf's clothing; a case of renal leiomyoma masquerading as hereditary leiomyomatosis and renal cell carcinoma

Introduction: Active surveillance has become a standard of care for the management of small renal masses. Decision to transition from surveillance to intervention relies on several factors including growth kinetics, histologic grade on biopsy and patient comorbidities. Management of renal masses in pregnancy presents a unique change when clinical triggers must be weighed with risk to fetus. We pre...
Posted 3 months ago

Biomedical

Group plus “mini” individual pre-test genetic counselling sessions for hereditary cancer shorten provider time and improve patient satisfaction

Background Genetic counselling (GC) is an integral component in the care of individuals at risk for hereditary cancer predisposition syndromes (CPS). In many jurisdictions, access to timely counselling and testing is limited by financial constraints, by the shortage of genetics professionals and by labor-intensive traditional models of individual pre and post-test counselling. There is a need for...
Posted 3 months ago

Biomedical

Meeting abstracts from the Annual Conference “Clinical Genetics of Cancer 2022”

...
Posted 3 months ago

Biomedical

Hereditary Cancer Syndromes: Identifying and Managing High-Risk Patients

Hereditary Cancer Syndromes: Identifying and Managing High-Risk Patients...
Posted 3 months ago

Biomedical

Current status of inherited pancreatic cancer

Background It is estimated that about 10% of pancreatic cancer cases have a genetic background. People with a familial predisposition to pancreatic cancer can be divided into 2 groups. The first is termed hereditary pancreatic cancer, which occurs in individuals with a known hereditary cancer syndrome caused by germline single gene mutations (e.g.,BRCA1/2,CDKN2A). The second is considered as fami...
Posted 3 months ago