Research Infinity - All Articles

Biomedical

Current and Potential Therapies Targeting Inflammation in NASH

Nonalcoholic steatohepatitis (NASH) is the advanced form of nonalcoholic fatty liver disease (NAFLD). It is characterized by hepatic steatosis, inflammation, hepatocellular injury, and fibrosis. Inflammation plays a key role in the progression of NASH and can be provoked by intrahepatic (e.g., lipotoxicity, immune responses, oxidative stress and cell death) and extrahepatic sources (adipose tissue...
Posted 2 months ago

Biomedical

Inflammatory Signaling and Brown Fat Activity

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Posted 2 months ago

Biomedical

DHEAS and Human Development: An Evolutionary Perspective

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Posted 2 months ago

Biomedical

Adipocyte-Endothelium Crosstalk in Obesity

Obesity is characterized by pathological adipose tissue (AT) expansion. While healthy AT expansion enhances systemic insulin sensitivity, unhealthy AT expansion through increased adipocyte size is associated with insulin resistance, fibrosis, hypoxia, and reduced adipose-derived adiponectin secretion. The mechanisms causing the unhealthy AT expansion are not fully elucidated; yet, dysregulated cro...
Posted 2 months ago

Physics Maths Engineering

Synthesis of Bisoxazole and Bromo-substituted Aryloxazoles

Herein, we report a bisoxazole derivative as well as a bromo-substituted oxazole derivatives via a simple approach. The synthesis begins with an inexpensive and readily available starting material, such as 2,5-dimethoxybenzaldehyde, hydroquinone, and p-toluenesulfonylmethyl isocyanide (TosMIC). This approach relies on the Van Leusen oxazole method and electrophilic aromatic bromination. The struct...
Posted 2 months ago

Biomedical

Distribution and Metabolic Activities of Marine Microbes in Response to Natural and Anthropogenic Stressors

As a consequence of climate change and increased human pressure, aquatic ecosystems are experiencing natural and anthropogenic stressors and events such as temperature warming, acidification, biodiversity loss, and degraded water quality [...]...
Posted 2 months ago

Biomedical

The Roles of Various Immune Cell Populations in Immune Response against Helminths

Helminths are multicellular parasites that are a substantial problem for both human and veterinary medicine. According to estimates, 1.5 billion people suffer from their infection, resulting in decreased life quality and burdens for healthcare systems. On the other hand, these infections may alleviate autoimmune diseases and allergy symptoms. The immune system is programmed to combat infections; n...
Posted 2 months ago

Physics Maths Engineering

Heavy-Tailed Probability Distributions: Some Examples of Their Appearance

We provide two examples of the appearance of heavy-tailed distributions in social sciences applications. Among these distributions are the laws of Pareto and Lotka and some new ones. The examples are illustrated through the construction of suitable toy models....
Posted 2 months ago

Biomedical

Development of Ornithology and Ornithological Journals—A New Opening by the MDPI with the Birds Journal

Before I started to produce this Editorial article for the new ornithological open access journal, Birds, of the MDPI (Multidisciplinary Digital Publishing Institute), I read a fascinating book about the history of ornithology by Michael Walters [...]...
Posted 2 months ago

Biomedical

Software Development for Processing and Analysis of Data Generated by Human Eye Movements

This research focuses on a software application providing opportunities for the processing and analysis of data generated by a saccade sensor with human eye movements. The main functional opportunities of the developed application are presented as well. According to the methodology of the experiments, three experiments were prepared. The first was related to visualization of the stimuli on a stimu...
Posted 2 months ago