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Biomedical

Synthesis of Bisoxazole and Bromo-substituted Aryloxazoles

Herein, we report a bisoxazole derivative as well as a bromo-substituted oxazole derivatives via a simple approach. The synthesis begins with an inexpensive and readily available starting material, such as 2,5-dimethoxybenzaldehyde, hydroquinone, and p-toluenesulfonylmethyl isocyanide (TosMIC). This approach relies on the Van Leusen oxazole method and electrophilic aromatic bromination. Th...
Posted 1 week ago

Physics Maths Engineering

Distribution and Metabolic Activities of Marine Microbes in Response to Natural and Anthropogenic Stressors

As a consequence of climate change and increased human pressure, aquatic ecosystems are experiencing natural and anthropogenic stressors and events such as temperature warming, acidification, biodiversity loss, and degraded water quality [...]...
Posted 1 week ago

Biomedical

The Roles of Various Immune Cell Populations in Immune Response against Helminths

Helminths are multicellular parasites that are a substantial problem for both human and veterinary medicine. According to estimates, 1.5 billion people suffer from their infection, resulting in decreased life quality and burdens for healthcare systems. On the other hand, these infections may alleviate autoimmune diseases and allergy symptoms. The immune system is programmed to combat infec...
Posted 1 week ago

Biomedical

An Overview of the Epigenetic Modifications in the Brain under Normal and Pathological Conditions

Epigenetic changes are changes in gene expression that do not involve alterations to the DNA sequence. These changes lead to establishing a so-called epigenetic code that dictates which and when genes are activated, thus orchestrating gene regulation and playing a central role in development, health, and disease. The brain, being mostly formed by cells that do not undergo a renewal process...
Posted 1 week ago

Biomedical

Prevalence of Leishmaniasis among Blood Donors: A Systematic Review and Meta-Analysis

Our study seeks to provide a comprehensive assessment of leishmaniasis prevalence among blood donors, employing rigorous methodologies to inform public health initiatives and transfusion safety measures. A thorough literature search was conducted using electronic databases (Medline, Scopus, Web of Science, and Google Scholar) to identify the relevant studies reporting the prevalence of lei...
Posted 1 week ago

Social Science

Determinants of Motivation to Work in Terms of Industry 4.0—The Gen Z Perspective

The mentality of Generation Z differs markedly from the approach to social and economic issues presented by earlier generations. These young people have had access to the internet and other innovative technologies since birth. A tape recorder or a floppy disk is a museum exhibit for them. They are unfamiliar with the everyday problems that citizens of Central and Eastern Europe faced durin...
Posted 1 week ago

Physics Maths Engineering

Heavy-Tailed Probability Distributions: Some Examples of Their Appearance

We provide two examples of the appearance of heavy-tailed distributions in social sciences applications. Among these distributions are the laws of Pareto and Lotka and some new ones. The examples are illustrated through the construction of suitable toy models....
Posted 1 week ago

Physics Maths Engineering

Novel Screen System Improvement Methodology for Flood and Diffuse Pollution Control: Demonstration via a Case Study

Screen systems are often neglected in practice. This can lead to local flooding, pollution of receiving watercourses, blockages of channels by debris, and safety problems for children playing. The aim of this case study is therefore to protect below-ground channels and people, prevent flooding, improve water quality, and save personnel costs through a new screen system maintenance, repair,...
Posted 1 week ago

Physics Maths Engineering

Applications of Machine Learning to the Study of Crystalline Materials

This Special Issue, “Applications of Machine Learning to the Study of Crystalline Materials”, is a collection of seven original articles published in 2021 and 2022 and dedicated to applications of machine learning in materials research [...]...
Posted 1 week ago

Social Science

Dynamics of Health Financing among the BRICS: A Literature Review

Despite economic progress, government efforts, and increased healthcare investments, health deprivation continues to persist in the countries of Brazil, Russia, India, China, and South Africa (BRICS). Hence, addressing the growing demand for health financing in a sustainable way and adopting unique approaches to healthcare provision is essential. This paper aims to review publications on t...
Posted 1 week ago

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