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Biomedical

Traumatic penile amputation: a case report

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Posted 1 month ago

Biomedical

A review of reproducible and transparent research practices in urology publications from 2014 to2018

Abstract Background Reproducibility is essential for the integrity of scientific research. Reproducibility is measured by the ability of different investigators to replicate the outcomes of an original publication using the same materials and procedures. Unfortunately, reproducibility is not current...
Posted 1 month ago

Biomedical

Seminal papers in urology: two-year outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for refractory urgency urinary incontinence: a Randomized Trial

AbstractIn this critical review, we explore the study design, strengths and limitations of the paper: “Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: A Randomized Trial.” The paper reports 24 month follow-up data of the landmark ROSETTA trial. This multi-centre, open-labelled parallel randomise...
Posted 1 month ago

Biomedical

Prediction of biochemical recurrence after laparoscopic radical prostatectomy

Abstract Background Radical prostatectomy (RP) has been considered primary treatment for localized prostate cancer. Biochemical recurrence (BCR) occur approximately 20–30% in five year after RP. We aim to develop a novel nomogram to predict BCR-free survival (BCRFS) and performed external validati...
Posted 1 month ago

Biomedical

Does the biomarker search paradigm need re-booting?

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Posted 1 month ago

Biomedical

Symptomatic renal papillary varicosities and medullary nephrocalcinosis

Abstract Background Nephrocalcinosis is often asymptomatic but can manifest with renal colic or hematuria. There is no reported association between nephrocalcinosis and renal vascular malformations, which may also be a source of hematuria. We herein present a case of a patient with hematuria related...
Posted 1 month ago

Biomedical

An uncommon mimicker of renal malignancy: IgG4-related disease

Abstract Background Increased usage of cross sectional imaging for a variety of indications, in particular CT imaging, has led to an increased detection of renal and ureteric masses. Benign ureteric masses are rare, with 95% of identified tumours consisting of transitional cell carcinoma (TCC). IgG4...
Posted 1 month ago

Biomedical

Seminal papers in urology: anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence

AbstractIn this critical review, we explore the study design, strengths, and limitations of landmark trial “Anticholinergic therapy vs. onabotulinumtoxinA for urgency urinary incontinence”. This trial was the first to directly compare two key treatment options for urge urinary incontinence – anticholinergic medication and intravesical botox, and still influen...
Posted 1 month ago

Social Science

Scientific Evidence for the Effectiveness of Mangrove Forests in Reducing Floods and Associated Hazards in Coastal Areas

The evidence for the capacity of mangrove forests for coastal protection gained more importance within the recent decade because of important international agreements, such as the Sustainable Development Goals and Sendai Framework for Disaster Risk Reduction. However, the degree to which researchers agree on the capacity of mangroves to reduce coastal hazards is not fully established. This...
Posted 1 month ago

Biomedical

Acetazolamide for Bipolar Disorders: A Scoping Review

Acetazolamide, a carbonic anhydrase inhibitor, is used to treat a variety of ailments. It has been highlighted for its potential to benefit people with bipolar disorders, for whom there are clear current unmet treatment needs. This scoping review sought to synthesise all available evidence related to the potential effects of acetazolamide on symptoms related to bipolar disorder, acceptabil...
Posted 1 month ago

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