Biomedical
Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought by interferon pathway activation. Herein, we connote the mechanisms behind this phenomenon and discuss its implications in age-related pathology.
Interferons are part of the immune defense against viral infections. However, their chronic activation in aging tissues can lead to detrimental effects, contributing to age-related pathologies by promoting inflammation and cellular changes. :contentReference[oaicite:1]{index=1}
Persistent interferon signaling in aging tissues can lead to inflammation and cellular changes that contribute to age-related pathologies. :contentReference[oaicite:2]{index=2}
Understanding the relationship between interferon responses and aging is crucial for developing interventions that modulate interferon signaling to mitigate aging-related diseases. :contentReference[oaicite:3]{index=3}
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Total | 263 | 263 |
Show by month | Manuscript | Video Summary |
---|---|---|
2025 April | 1 | 1 |
2025 March | 63 | 63 |
2025 February | 40 | 40 |
2025 January | 50 | 50 |
2024 December | 43 | 43 |
2024 November | 48 | 48 |
2024 October | 18 | 18 |
Total | 263 | 263 |