Physics Maths Engineering
Highlights
• Prediction interval has a great potential to be used in laboratory medicine
• It is a powerful tool for computing personalized reference interval and reference change value
• It can be used to assess the stability of analytical systems
• It can be used in monitoring the accuracy and reproducibility of analytical systems
Monitoring is indispensable for assessing disease pr...
Posted 5 months ago
Physics Maths Engineering
Researchers and practitioners are typically familiar with descriptive statistics and statistical inference. However, outside of regression techniques, little attention may be given to questions around prediction. In the current paper, we introduce prediction intervals using fundamental concepts that are learned in descriptive and inferential statistical training (i.e., sampling error, standard dev...
Posted 5 months ago
Highlights
• Biological fluids contain nano-sized particles called extracellular vesicles
• Extracellular vesicles properties reflect the physiological and pathological state of the parent cells
• Extracellular vesicles as analytes are suitable for use in liquid biopsy-based real-time diagnostics
• Glycans, complex oligosaccharides, are distinct components of extracellular vesicles mem...
Posted 5 months ago
Introduction
Reliable and accurate measurement of blood glucose concentration is of crucial importance for making clinical decisions in diagnosis diabetes, gestational diabetes and impaired fasting glucose tolerance.
Materials and methods
Survey was performed in form of questionnaire. Questionnaire was sent to all Croatian laboratories (N = 204) in electronic form using SurveyMonkey cloud-bas...
Posted 5 months ago
It’s been 10 years now from the debut of clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) era in which gene engineering has never been so accessible, precise and efficient. This technology, like a refined surgical procedure, has offered the ability of removing different types of disease causing mutations and restoring key proteins activity with ease of...
Posted 5 months ago
Mustapha Zendjabil
Mustapha Zendjabil
Faculty of Medicine, University of Oran 1 - Ahmed Ben Bella, Oran, Algeria
Highlights
• Methods used for miRNAs expression profiling are quantitative reverse transcription polymerase chain reaction, microarrays, next generation sequencing and droplet digital PCR
• To obtain reproducible and accurate miRNAs expression profiling detection, it is crucial to strictly standardize the entire process, starting from choosing the specimen type until the normalization strate...
Posted 5 months ago
Highlights
• Antiphospholipid syndrome is a rare systemic autoimmune disease characterized by recurrent pregnancy morbidity or thrombosis in combination with the persistent presence of antiphospholipid antibodies in plasma/serum
• Specialists in laboratory medicine should take responsibility for the entire analytical process, so that possible interferences are minimized, and physicians obtai...
Posted 5 months ago
Physics Maths Engineering
Nwosu and Ogbu (2011) provide a comprehensive overview of the challenges posed by climate change to livestock production in Nigeria. They emphasize the need for adaptive measures to address the adverse effects of climate variability on livestock health and productivity. The review underscores the importance of integrating environmental modifications, selective breeding, and nutritional adjustme...
Posted 5 months ago
Melissa J. L. Bonorden,
Melissa J. L. Bonorden
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
Michael E. Grossmann,
Michael E. Grossmann
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
Sarah A. Ewing,
Sarah A. Ewing
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
Olga P. Rogozina,
Olga P. Rogozina
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
Amitabha Ray,
Amitabha Ray
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
Katai J. Nkhata,
Katai J. Nkhata
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
D. Joshua Liao,
D. Joshua Liao
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
Joseph P. Grande,
Joseph P. Grande
Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
Margot P. Cleary
Margot P. Cleary
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA
To clarify effects of diet and body weight on prostate cancer development, three studies were undertaken using the TRAMP mouse model of this disease. In the first experiment, obesity was induced by injection of gold thioglucose (GTG). Age of prostate tumor detection (~33 wk) and death (~43 wk) was not significantly different among the groups. In the second study, TRAMP-C2 cells were injected i...
Posted 5 months ago
Peak oxygen uptake (VO2), evaluated as exercise tolerance, is a strong predictor of life prognosis regardless of health condition. Several previous studies have reported that peak VO2 is higher in those with a greater decrease in muscle oxygen saturation (SmO2) in the active muscles during incremental exercise. However, the skeletal muscle characteristics of individuals exhibiting a greater decrea...
Posted 5 months ago
