Research Infinity - All Articles

Physics Maths Engineering

Bias estimation for Sigma metric calculation

I read with great interest the study of Keleş on the evaluation of analytical performances of clinical chemistry assays using the Six Sigma methodology (1). The author has computed Sigma metrics according to their laboratory performance as well as the manufacturer’s data in the reagent package inserts. For Sigma metric calculation according to laboratory performance, the author has estimated...
Posted 5 months ago

Biomedical

The apparent prevalence, the true prevalence

Serologic tests are important for conducting seroepidemiologic and prevalence studies. However, the tests used are typically imperfect and produce false-positive and false-negative results. This is why the seropositive rate (apparent prevalence) does not typically reflect the true prevalence of the disease or condition of interest. Herein, we discuss the way the true prevalence could be derived fr...
Posted 5 months ago

Biomedical

Laboratory medicine in arterial hypertension

In the initial diagnostics of arterial hypertension (AH) laboratory medicine is a cornerstone, along with a blood pressure (BP) measurement and an electrocardiogram. It mainly refers to routine blood and urine tests for diagnosis and monitoring primary hypertension and its associated conditions such as asymptomatic hypertension-mediated organ damage, chronic kidney disease and hypertensive disorde...
Posted 5 months ago

Biomedical

Underfilled blood tube containing EDTA

Introduction Blood samples having inappropriate volume are a substantial part of preanalytical errors. Inadequate sample volume for glycated haemoglobin (HbA1c) test may be a common problem of patients with diabetes mellitus having vascular changes. In this study, we compared HbA1c concentrations of underfilled and appropriately filled blood collection tubes. Materials and methods To compare Hb...
Posted 5 months ago

Biomedical

Considering Value in Prescribing and Deprescribing for Older Adults

Physicians know how easy it is to start a medication for a chronic condition in older adults. Often, these medications have marginal benefits and substantial potential harms and can be difficult to stop once started. Many older patients receive multiple medications with potential interactions and harms, which can be costly and is sometimes referred to as financial toxicity from treatment. Yet the ...
Posted 5 months ago

Biomedical

Gait and Cognitive Declines in Dementia—Double or Nothing

Summary

The article "Gait and Cognitive Declines in Dementia—Double or Nothing" by Joe Verghese (2022) discusses the interrelationship between gait performance and cognitive decline in dementia. It emphasizes that impairments in gait are often observed early in the course of dementia and that changes in gait speed can serve as early indicator...
Posted 5 months ago

Biomedical

Programmatic Implications of a Revised Classification System for Undernutrition

Gausman et al argue that multiple measures of anthropometric failure (AF) are needed to assess undernutrition in the country context and design public health and nutrition programs to reach the most economically disadvantaged children younger than 5 years. But in practice, how can programs use information on AF to improve delivery of crucial interventions?

Biomedical

Effects of Electroacupuncture for Depression-Related Insomnia

Summary

The article "Effects of Electroacupuncture for Depression-Related Insomnia" by Albert Yeung and David Mischoulon (2022) investigates the efficacy and safety of electroacupuncture (EA) in treating insomnia associated with depression. The study involved 270 patients who were randomly assigned to one of three groups: EA treatment combined...
Posted 5 months ago

Biomedical

Metabolic Surgery in Patients With High BMI and Obesity

The article "Metabolic Surgery in Patients With High BMI and Obesity" by Magnus Sundbom (2024) examines the role of metabolic surgery in individuals with a high body mass index (BMI) and obesity. The study highlights that metabolic surgeries, such as laparoscopic gastric bypass and sleeve gastrectomy, have become standard treatments for severe obesity (BMI ≥35). These procedures have demonstrate...
Posted 5 months ago

Biomedical

Blood Bonds: Transforming Blood Donation Through Innovation, Inclusion, and Engagement

The journey of receiving blood as a patient with transfusion-dependent beta thalassemia has profoundly shaped my understanding of the life-saving power of blood donation. This personal experience underscores the critical importance of blood donors, not just for individual recipients but for the broader community, enhancing public health, productivity, and well-being. There are several challenges t...
Posted 5 months ago